Adapting EPA Method 8330B for Analysis of Explosives in Water to SPE and LC/MS/MS Authors
نویسندگان
چکیده
EPA Method 8330B for trace explosives in water by HPLC was transferred from UV detection to mass spectrometry detection using the Agilent 1290 Infinity LC System coupled to the Agilent 6460 Triple Quadrupole LC/MS System using APCI negative mode. Eleven explosive compounds were analyzed with this method at trace concentrations in water samples with limits of detection at the 5–50 ng/L concentration level. Solid phase extraction (SPE) was used and both a C18 and a polymeric cartridge were tested for recoveries. The polymeric cartridge gave the highest recoveries, from 80–101% using off-line SPE. The combination of UHPLC and the 6460 Triple Quadrupole LC/MS System is an effective method for measuring explosives in water.
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